Forbidden CIN
نویسندگان
چکیده
منابع مشابه
The wages of CIN
Aneuploidy and chromosome instability (CIN) are hallmarks of the majority of solid tumors, but the relationship between them is not well understood. In this issue, Thompson and Compton (Thompson, S.L., and D.A. Compton. 2008. Examining the link between chromosomal instability and aneuploidy in human cells. J. Cell. Biol. 180:665-672) investigate the mechanism of CIN in cancer cells and find tha...
متن کاملPaola Dal Cin
Double minutes (dmin) and homogeneously staining regions (hsr) are the cytogenetic hallmarks of genomic amplification in cancer, more common in solid tumors than in hematologic malignancies. Double minute chromosomes are seen primarily in acute myeloid leukemia, with amplification of the MYC oncogene or, less frequently, the MLL transcription factor (Rayeroux and Campbell 2009). Both normal and...
متن کاملLEEP Verses Cryotherapy in CIN.
OBJECTIVE To compare the effectiveness and safety profile of LEEP (Loop Electrosurgical Excision Procedure) verses cryotherapy in the treatment of CIN. MATERIAL AND METHOD Women with abnormal pap smears were subjected to VIA and VILLI followed by colposcopy. A total of 200 cases were included in this prospective study. Once the diagnosis of CIN was confirmed on histopathology, the women were ...
متن کاملChronical cervical infections and dysplasia (CIN I, CIN II): Vaginal vitamin D (high dose) treatment
In a small praxis/ambulance study we evaluated data of 200 women with chronical recurrent cervical infections and with a cervix dysplasia (CIN 1, CIN 2). who got after the primary therapy a treatment with vitamin D vaginal suppositories (12.500 IU, 3 nights a week, for 6 weeks). We found that - when compared with the lactobacillus vaginal suppositories - the high dose vitamin D vaginal treatmen...
متن کاملForbidden Vertices
In this work, we introduce and study the forbidden-vertices problem. Given a polytope P and a subset X of its vertices, we study the complexity of linear optimization over the subset of vertices of P that are not contained in X . This problem is closely related to finding the k-best basic solutions to a linear problem. We show that the complexity of the problem changes significantly depending o...
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ژورنال
عنوان ژورنال: Nature Reviews Cancer
سال: 2010
ISSN: 1474-175X,1474-1768
DOI: 10.1038/nrc2813